Grünenthal uses its own and third-party cookies to improve the browsing experience, offer personalized content and improve its services. We use analytics scripts which set a tracking cookie, but we will activate these services only with your consent. If you press the button “Accept”, you consent to the use of these analytics scripts.

You can withdraw your consent at any time. To do so, please modify your configurations on this website by following this link to our privacy statement with the configuration options: Go to settings

I'm ok with this



Pain education is a crucial step in improving the standard of care in pain management. We hope that CHANGE PAIN® helps healthcare professionals to stay up to date with the latest data and recommendations for the diagnosis, treatment and management of pain.

... Read More

"Each individual has the right to avoid as much suffering
and pain as possible, in each phase of his or her illness"

Learn about European charter of patients' rights

Pain Basics

Pain Conditions


Chronic low back pain

Chronic low back pain is a leading cause of disability, with a pronounced impact on quality of life, and major economic and societal consequences. In this article you can learn about the assessment of chronic low back pain, and the range of treatment options available.

Find out more


Chronic post-surgical pain

Chronic post-surgical pain (CPSP) is a poorly recognised potential outcome of surgery, which can result in potentially devastating outcomes for the individual affected. In this article you can learn about how to assess for CPSP and gain insights from the latest management guidelines and recommendations.

Find out more


Cluster headache

Cluster headache is a rare but excruciating condition, characterised by sharp pain on one side of the head, that can occur up to eight times a day during an episode. In this article you can learn about the key triggers and symptoms of cluster headache, and how it can be managed.

Find out more


Complex regional pain syndrome

Complex regional pain syndrome (CRPS) is a rare condition presents with painful autonomic and inflammatory features, typically occurring after trauma to a limb. In this article you can learn about how to recognise CRPS and identify possible treatment options.

Find out more



Fibromyalgia is the most common widespread pain condition, characterised by chronic widespread pain and joint stiffness. In this article you can learn about the systemic symptoms that accompany fibromyalgia, and about the latest treatment recommendations for this condition.

Find out more



Migraines represent the sixth most common cause of disability on the planet and affect over a billion people each year. In this article, you can learn about how migraines develop and associated common triggers, as well as key strategies for prevention and treatment.

Find out more



Osteoarthritis is the most common degenerative joint disease, affecting 25% of the adult population. In this article you can learn about modifiable and non-modifiable risk factors, as well as pain management options available for individuals affected.

Find out more


Peripheral neuropathic pain

Peripheral neuropathic pain (PNP) is a particularly distressing chronic pain syndrome that can develop after a lesion or disease affects the peripheral somatosensory nervous system. In this article you can learn about the diverse causes of PNP and how to manage symptoms.

Find out more


Neuropathic low back pain

The neuropathic component of chronic back pain is under-recognised and can cause significant physical disability, as well as be a burden on patients and healthcare systems. In this article, you can read about signs and symptoms to be vigilant for, as well as tools that can help to differentiate the neuropathic component of chronic back pain from other types of pain.

Find out more


Cancer related neuropathic pain

Cancer-related neuropathic pain (CRNP) is estimated to affect nearly two-fifths of patients with cancer. In this article, you can learn more about the causes of CRNP (e.g. chemotherapy), its signs and symptoms, and methods of diagnosis. You can also find links to the latest management guidelines.

Find out more

Pain basics

Chronic pain is complex and multifaceted in nature and is recognised as a disease in its own right. This article introduces the essentials behind pain, including underlying disease mechanisms, comprehensive assessment and the management options available.

Find out more

CHANGE PAIN meeting in a box
CHANGE PAIN® 'Meeting-in-a-box'
Run your own meeting on chronic pain, focussed on the pathophysiology, diagnosis, assessment and treatment of specific pain populations and conditions.

30-Minute challenge: Neck pain: Functional recovery and how to manage it

We are delighted to invite you to the sixth 30-minute expert talk challenge webinar of the series, focusing on neck pain, functional recovery and how to manage it. Who will Prof. Dr Frank Huygen challenge for this one? More details will follow soon! 


  • 14 Oct, 2021
  • English
  • 60 minutes
  • Upcoming webinars


  • Prof. Dr Ralf Baron

30-Minute challenge: Complex regional pain syndrome (CRPS): Tailored treatment based on phenotyping

Prof. Dr Frank Huygen has accepted Prof. Dr Charles Argoff's challenge and will be presenting on tailored treatments for CRPS based on phenotyping. This will be followed by an audience Q&A session.

  • 23 Sep, 2021
  • English
  • 60 minutes
  • Upcoming webinars


  • Prof. Dr Ralf Baron
Pain Alliance Europe logo